Prof. Young-Ho Lee: autologous cord blood is helpful in treating children with cerebral palsy
Meet the Professor

Prof. Young-Ho Lee: autologous cord blood is helpful in treating children with cerebral palsy


Received: 17 July 2017; Accepted: 03 August 2018; Published: 16 August 2018.

doi: 10.21037/aob.2018.08.02


Expert introduction

Prof. Young-Ho Lee (Figure 1) is a Professor of Department of Pediatrics, Hanyang University Medical Center. He earned his degree of MD and PhD at Hanyang University College of Medicine. He got postgraduate researcher course in the field of pediatric hematology and stem cell transplantation at the UCLA Medical Center. His major fields are pediatric hematology, hematopoietic stem cell transplantation, and stem cell biology including stem cell homing. He performed the first successful cord blood transplantation (CBT) for child with relapsed acute leukemia at 1998 in Korea. Since then, he established infrastructures of CBT regarding banking guidelines for CB as well as clinical guideline for CBT. Furthermore, he performed the pioneering works for legislation for CB act in Korea. Recently, he has tried the application of mononuclear cells of CB and mobilized peripheral blood stem cells as cell therapeutics for refractory neurologic diseases.

Figure 1 Young-Ho Lee, MD, PhD. Professor, Hanyang University Medical Center, Seoul, Korea.

Editor’s note

The 6th China Cord Blood Symposium was held during June 29th, 2018 to July 1st, 2018 in Guangzhou. During the meeting, we invited Prof. Young-Ho Lee from Korea to have an interview.

In the interview (Figure 2), Prof. Lee said that in South Korea, the incidence of cerebral palsy is not high, and only about one in 1,000 cases of childbirth suffers from cerebral palsy. Currently, supportive care is the main treatment for cerebral palsy, including physical therapy.

Figure 2 Professor Young-Ho Lee: autologous cord blood is helpful in treating children with cerebral palsy (1). Available online: http://www.asvide.com/article/view/26461

When it comes to the treatment of cerebral palsy with autologous cord blood, Prof. Lee pointed out that cord blood has a nerve regeneration effect. The use of cord blood helps them improves their nerves. Prof. Lee gave us a brief introduction to a previous study. His team used cord blood cell therapy for cerebral palsy patients, and about 25% of patients have responded to autologous cord blood transfusions. Therefore, we can expect more clinical experience, which increases the clinical outcome of cord blood cell therapy for patients with cerebral palsy.

In order to improve the further development of patients with cerebral palsy by using cord blood, Prof. Lee hopes to study the method of cord blood treatment of cerebral palsy in the future, so that this treatment method can bring better therapeutic effects to more children with cerebral palsy. He believes that cord blood will be very beneficial for the treatment of children with cerebral palsy.


Interview questions

  • What is the incidence of cerebral palsy?
  • What are the treatments for cerebral palsy?
  • Compared to other treatments, what are the advantages of adopting “autologous cord blood reinfusion” in treating cerebral palsy?
  • Is there any improvement for autologous cord blood to treat cerebral palsy?
  • What do you think of the future development of treating cerebral palsy by adopting autologous cord blood in Korea?

Acknowledgements

None.


Footnote

Conflicts of Interest: The author has no conflicts of interest to declare.


References

  1. Tang C. Professor Young-Ho Lee: autologous cord blood is helpful in treating children with cerebral palsy. Asvide 2018;5:688. Available online: http://www.asvide.com/article/view/26461

(Science Editor: Constance Tang, AOB, aob@amegroups.com)

doi: 10.21037/aob.2018.08.02
Cite this article as: Tang C. Prof. Young-Ho Lee: autologous cord blood is helpful in treating children with cerebral palsy. Ann Blood 2018;3:35.